Use of Multislice CT in Evaluation of Different Grades of COVID 19 Patients in Addition to Correlation with Serum Ferritin Level: A Cross Sectional Study

Abstract Background: During the worldwide COVID 19 pandemic, both labs and Computed tomography play an important role as prognostic factors for disease severity. Ferritin, the cellular protein storage for iron, is an indicator for systemic inflam-mation and computed tomography shows characteristic pul-monary changes in COVID 19 patients. Aim of Study: The target of this study is to assess the role of Ferritin and computed tomography in evaluation of mild, moderate and severe COVID 19 patients and to correlate between ferritin level, CT findings and disease severity. Patients and Methods: Between first of July till end of September 2020, 75 patients (21 males and 54 females) with PCR confirmed COVID-19 infection from Cairo, Egypt, were referred for laboratory and multislice computed tomographic assessment. Results: The most prominent radiological findings in moderate and severe cases were ground glass opacities (54.2% and 89.5%), lung nodules (54.2% and 52.6%) and reticular pattern (37.5% and 52.6%) respectively. Some imaging features like ground glass opacities, interlobular septal thickening and pleural effusion with elevated ferritin levels were shown to correlate with disease severity. Conclusion: Computed tomography and serum ferritin levels have a significant role in evaluation and assessment of severity of patients with COVID 19.