Retrospective Comparative Study of Total Repair of Partial Atrioventricular Canal Before and After Two Year Old Age

Abstract Background: The spectrum of atrioventricular septal defects account for about 7-17% of congenital heart disease, and 25% of them are partial atrioventricular canal defects (2). The repair of partial atrioventricular canal are preferred to be performed when diagnosed and before an operation might interfere with school. According to the long-term follow-up results of other centers, surgical outcomes were excellent. There were many reports about the surgery outcomes of patients in young age. The aim of this retrospective study is to review the results of treating infants with partial atrioven-tricular canal patients in our center. The mortality rate, reop-eration rate, surgery procedures and valve regurgitation associated data were described. Aim of Study: To evaluate the outcomes of patients under-going surgical repair of partial atrioventricular septal defect (AVSD) and analyzed the effect of age on outcome. Objective is to assess the best time of repair in this congenital cardiac anomaly and to study different postoperative clinical pathways. Patients and Methods: This study is a Retrospective cohort study. This retrospective cohort study was carried out on 75 patients with successfully surgical PAVC repair patients were recruited from cardiothoracic department, Ain shams and affiliated Hospitals. From October 2022 to March 2023 and the operation done for these patients two years ago and collected data eight months. After undergoing ECHO which is the standard for such patients for follow-up during the study period (6 months). All patients were given informed consent. The study protocol was approved by the ethical committee, Faculty of Medicine, Ain Shams University Hospitals, Cardi-othoracic Department. Results: Regarding the baseline characteristic between in children 24 months among study groups, we found that age ranged 4-190 months (>24m 61.3% –<24m 38.7%). Sex male 57.3% more affected than female 42.7%. Weight range 4-60 Kg. NICU admission 8%. Other congenital anomalies 4%. Thrombocytopenia 1.3%. ASD size 4-26mm. Pulmonary HTN 56%. LV dilation 1.3%. RA dilation 41.3%. EF range 55-82. Regarding the comparison of demographic characteristic between in children with age more and less than 24 months among study groups, we found that there was statistically difference between more and less than 24 months in age, weight (p-value 0.001, >0.001 respectively). Conclusion: Age ranged 4-190 months (>24m 61.3% - <24m 38.7%). Sex male 57.3% more affected than female 42.7%. Weight range 4-60Kg. NICU admission 8%. Other congenital anomalies 4%. Thrombocytopenia 1.3%. ASD size 4-26mm. Pulmonary HTN 56%.LV dilation 1.3%. RA dilation 41.3%. EF range 55-82. Mitral regurge mild, moderate and severe (14.7%, 33.3%, 52%). Tricuspid regurge mild, moderate and severe (24%, 42.7%, 33.3%). There was statis-tically difference between more and less than 24 months in age, weight (p-value 0.001, >0.001 respectively). There was statistically difference between more and less than 24 months in pulmonary hypertension and EF (p-value 0.043, 0.003 respectively).