Role of Anticoagulation in Reducing Post Operative DVT Following Major L.L Amputation (Prospective Clinical Trial)

Abstract Background: Postoperative vein clots. Aim of Study: The aim of the study: was to estimate the role of Anticoagulation in Reducing Post-Operative DVT Following Major L.L Amputation. Patients and Methods: The current study was carried on 35 patients whom underwent lower limb amputation and followed up for incidence of DVT. They were divided into two groups according to occurrence of DVT: No DVT group (n = 22), DVT group (n = 13). The expected period of the study is 6 months, started from January 2024 to June 2024. Results: There is no significant difference in age between the groups with and without deep vein thrombosis (DVT). The no-DVT group consists of 50% females and 50% males, while the DVT group has 46.2% females and 53.8% males. The mean BMI for the group without DVT is 27.69, compared to the DVT group with a mean BMI of 32.67. A significant difference in the distribution of smokers and non-smokers between the groups There is statistically significant difference in the incidence of DVT between the two surgery levels. There is statistically sig-nificant difference in the causes of amputation between the two groups. there is no statistically significant difference in the side of amputation between the two groups. Out of the 13 patients with DVT, the femoral segment was affected in 53.8% of cases. The popliteal segment was involved in 38.5% of cases, while the femoropopliteal segment was the least affected, with only 7.7% of cases. At 3 weeks, 69.2% of the patients (9 out of 13) were observed to have DVT, while 30.8% (4 out of 13) did not exhibit signs of DVT. However, by 8 weeks, the situation ap-pears to reverse, with the majority (69.2%) no longer showing signs of DVT and only 30.8% still having DVT. There is statis-tically significant difference between the two groups regarding the distribution of DVT venous segments. Conclusion: The study results-suggests that patients with above-knee amputations are more likely to experience DVT in the femoral segment compared to those with below-knee ampu-tations. The high incidence of DVT in patients who underwent AKA is probably because the femoral vein is a conduction ves-sel with few tributaries, a feature that leads to poor venous flow in its remnant segments and consequent thrombosis.