Impact of Vitamin D Deficiency on Diabetic Obese Patients with Non-Alcoholic Fatty Liver Disease

Document Type : Original Article

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The Departments of Internal Medicine*, Geriatric** and Clinical Pathology***, Faculty of Medicine, Ain Shams

Abstract

Background: Vitamin D is considered an extremely im-portant physiological regulator other than its classical role in skeletal homeostasis. There is growing evidence that connects vitamin D to liver disease. Aim of Study: Aim of this work is to study the clinical utili-ty of vitamin D among the diabetic obese patients and to assess the effect of vitamin D deficiency on NAFLD. Material and Methods: Our study was conducted on 150 older diabetic obese adult patients, patients were divided into two groups, group with normal vitamin level (NVDD) and group with decreased vitamin level (VDD). Both groups in-cluded a percent of NAFLD patients. Results: Highly significantly increased percentage of NAFLD in the group with vitamin D deficiency (VDD). Also, the prevalence of hyperlipidemia was higher in patients with vitamin D deficiency as compared to patients with a normal vitamin D. Conclusion: Vitamin D deficiency considered to be an im-portant risk factor for development of NAFLD.

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