Surgical Procedures Versus Catheter Intervention in Management of Adult Aortic Coarctation: A Meta-Analysis

Background: Coarctation of aorta refers to constriction of aorta, typically located just distal to left subclavian artery. Aim of Study: This study aimed to evaluate current litera-tures for the outcomes of surgery versus catheter intervention in treatment of adult patients of coarctation. Material and Methods: Systematic review, meta-analysis encompass randomized clinical trials, cohort studies, cross-sec-tional research. Methodological quality of each study was rig-orously evaluated, clarity in outcome measures, appropriate-ness in statistical analysis to ensure robustness of findings. Results: A meta-analysis of post-intervention outcomes after aortic coarctation repair found that catheter intervention had significantly lower mortality rates and persistent hyper-tension compared to surgical repair. Aneurysm formation fol-lowing catheter intervention was rare, with no heterogeneity. Re-intervention for recoarctation was slightly more common in catheter cases (10%) than in surgical repair (7.6%), with mod-erate heterogeneity. The findings suggest catheter intervention may be a preferable option due to lower mortality and persistent hypertension, though with a slightly higher need for re-inter-vention. The study highlights the need for more comprehensive and effective surgical interventions in aortic coarctation repair. Conclusion: Surgical repair and catheter-based interven-tions have positive long-term outcomes, but have unique chal-lenges. Surgical repair was related with persistent hypertension, despite fact that it has a higher mortality rate. Catheter-based interventions were less invasive, they were related with a high-er risk of aneurysm formation, re-interventions.