Can a Single-View Digital Breast Tomosynthesis Help in Characterizing Breast Asymmetries?

Background: Breast symmetry is a challenging mam mographic finding for radiologists. Digital breast tomosyn thesis (DBT) offers 3D imaging of the breast, reducing tissue superimposition and enhancing cancer detection. Digital breas tomosynthesis reduces false recalls and false-positive results especially in women with dense breast tissue. Single-view digital tomosynthesis has comparable accuracy to two-view tomosynthesis, but with the advantage of decreasing patien dose and better sensitivity and specificity compared to digita mammography. Aim of Study: We aimed to evaluate the diagnostic perfor mance of single-view digital breast tomosynthesis combined with digital mammography compared to digital mammography alone in assessing breast asymmetries. Patients and Methods: The study comprised 61 women with breast asymmetry who underwent full-field digital mam mography and single (MLO) view digital breast tomosynthesis Results: The diagnostic accuracy of digital mammography was 86.71%, with a sensitivity of 94.74% and a specificity of 71.43%. Using single-view DBT combined with mammogra-phy achieved a diagnosis accuracy of 78.69%, a sensitivity of 100%, and a specificity of 83.72%. Conclusion: Combining single-view digital breast tomo synthesis with digital mammography improves asymmetry characterization. It increases cancer diagnosis while decreasing the recall rate, improving specificity and sensitivity.