Assessment of Efficacy of Platelet-Rich Plasma Injection for Facial Rejuvenation

Abstract
Background: Facial rejuvenation includes different ther-apeutic modalities of returning facial youthfulness. PRP injection delivers very high concentrations of growth factors that lead to accelerated tissue regeneration and remodeling.
Aim of Study: The aim of this work was to evaluate the efficacy of single session of intradermal injection of autologous Platelet Rich Plasma (PRP) in facial rejuvenation.
Patients and Methods: 20 subjects with different types of facial wrinkles were included in this study. They were selected from Dermatology and Venereology Department, Tanta University Hospitals. All of them received single session of intradermal injection of autologous PRP and were clinically assessed before and 2 months after PRP injection using Wrinkle Severity Rating Scale (WSRS), Skin Texture Scale, and Subject Satisfaction Scale.
Results: All subjects showed significant clinical improve-ment of all types of facial wrinkles after PRP injection. At the end of follow-up period, there was statistically significant decrease in Wrinkle Severity Rating Scale (WSRS) comparable to that before PRP injection. Additionally, there was a statis-tically significant improvement of skin texture and subject satisfaction after PRP injection.
Conclusion: Intradermal injection of autologous PRP is well tolerated and capable of rejuvenating the face and pro-ducing a significant correction of different types of facial wrinkles.