Role of I-Scan in the Diagnosis of Patients with Portal Hypertensive Gastropathy

HANY SHEHAB, M.D., AYMAN YOUSY, M.D.;; MAGED EL-GHANAM, M.D., KHALED RAGAB, M.Sc.;; HAYTHAM ABDALLA, M.D., MOHAMED GODA, M.D.;; NOHA HELAL, M.D., TAREK ABOUSHOUSHA, M.D.;

doi:10.21608/mjcu.2018.55199

Role of I-Scan in the Diagnosis of Patients with Portal Hypertensive Gastropathy

Document Type : Original Article

Authors

The Departments of Endemic Medicine, Hepatology & Gastroenterology*, Faculty of Medicine, Cairo University, Hepatology & Gastroenterology** and Clinical Pathology***, Theodor Bilharz Research Institute

10.21608/mjcu.2018.55199

Abstract

Abstract
Background: Portal Hypertensive Gastropathy (PHG) occurs as a complication of cirrhotic or non-cirrhotic portal hypertension. PHG is clinically important because it might cause acute or chronic blood loss. The aim of the current study was to test the value of I-scan to predict gastric histologic diagnosis especially in cases with portal hypertensive gastrop-athy.
Subject and Methods: 113 subjects involved into this study and divided into two groups; Group (1) Consisted of twelve normal subjects while Group (2) Consisted of 101 HP negative PHG. Upper endoscopy was performed for all cases, first by WLE then we shifted to I-scan technology, two biopsies were taken (one from greater curvature of the body of stomach and the other from antrum). Also full clinical assessment, biochemical profile, viral markers and ultrasound were per-formed for all the patients.
Results: PHG group showed a congested SECN and CV of the body and antrum with high specificity and sensitivity above 90%.
Conclusion: I-scan has good sensitivity and specificity regarding diagnosis of PHG and poor specificity in the diag-nosis of HP gastritis.

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