Safety of Low Dose Atracurium Added to Lidocaine, Bupivacaine and Hyaluronidase Mixture in Percaruncular Peribulbar Anesthesia for High Myopes Undergoing Phacoemulsification (A Randomized Controlled Trial)

Document Type : Original Article

Authors

The Departments of Anesthesia, Pain Management & Surgical ICU* and Ophthalmology**, Faculty of Medicine, Cairo University

Abstract

Abstract
Background: The current study explored the safety of adding low dose atracurium to lidocaine, bupivacaine and hyaluronidase mixture in percaruncular peribulbar anesthesia for high myopes undergoing phacoemulsification.
Methods: 82 ASA-PS I-III patients scheduled for phacoe-mulsification with high myopia were enrolled in this rand-omized controlled double-blinded trial. The enrolled patients were randomly allocated to one of two groups. Group C (n=41) received 2.5ml of lidocaine 2%, 2.5ml of bupivacaine 0.5% with hyaluronidase 15IU/ml and 1ml normal saline, while patients in Group A (n=41) received the same mixture with 5mg atracurium. Patients' hemodynamics, peripheral O2 saturation, occurrence of intraoperative pain and incidence of were recorded.
Results: There were no major complications in any of the 82 cases. The incidence of minor complications between both groups were comparative. Chemosis occurred in 12.2% of Group A and in 24.3% of Group C. Sub-conjunctival hemor-rhage occurred in 4.9% of patients of both groups. Local hyperemia were only observed in Group A (7.3%) with no statistical significance.
Conclusion: Adding 5mg atracurium to LA solution did not increase the incidence of complications in percaruncular block in high myopes.

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The Medical Journal of Cairo University
Volume 86, March
March 2018
Pages 855-859

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