Association of Helicobacter Pylori Infection with Portal Hypertensive Gastropathy in Liver Cirrhosis

Document Type : Original Article

Authors

The Departments of Pathology* and General Medicine**, Faculty of Medicine, Sohag University

Abstract

Abstract
Background: Portal hypertensive gastropathy (PHG) is an important cause of morbidity in patients with Liver cirrhosis (LC). Helicobacter pylori (HP) infection is a common cause of gastritis and is an endemic disease in Egypt.
Aim of the Work: To study the presence of H. pylori infection in cases of LC with and without PHG.
Material and Methods: Fifty patients with LC including 25 cases with PHG and 25 cases without PHG who attended Sohag Faculty Hospital during the period 9/2016-3/2017 were examined for the presence of H pylori infection histologically using Hematoxyline and Eosin and Geimsa stains. The corre-lation between H pylori infection and the severity of PHG was studied statistically.
Results: H. pylori were detected in 76% of cases of LC (72% in LC with PHG and 80% of cases LC without PHG). Although there was an association between H pylori infection and the severity of PHG (5/7 cases), there was no statistically significant difference between H pylori infection and PHG.
Conclusion: H. pylori infection can be seen in cases of LC irrespective of the presence or absence of PHG more than in general population.

Keywords

The Medical Journal of Cairo University
Volume 86, June
June 2018
Pages 1281-1286

Files

Share

How to cite

Statistics