Impact of Variable Types of Preconditioning Upon Inotropic Score in Adult Patients Undergoing Cardiac Valve Replacement Surgery: A Randomized Clinical Trial

Document Type : Original Article

Authors

The Departments of Anesthesiology, Intensive Care & Pain Management* and Cardiothorathic Surgery**, Faculty of Medicine, Assiut University, Assiut, Egypt

Abstract

Abstract
Background: The objective of this study was to validate the impact of cardiac preconditioning (ischemic versus phar-macological) upon postoperative inotropic score in adult patient undergoing open heart surgery.
Aim of Work: Is to validate the impact of Sevoflurane versus ischemic & Sevoflurane pc upon postoperative inotropic score in adult patient undergoing open heart surgery.
Material and Methods: Thirty ASA II-IIIadult undergoing open heart surgery wereincluded in the study. They were randomly allocated into2 groups, Group A (15 patients). Anaesthetized by Sevoflurane as a pharmacologic precondi-tioner, Group B (15 patient) ischemic preconditioning was done after induction and before cardiopulmonary bypass by inflation the cuff of blood pressure above 200mmhg in the lower limb every 5min for 3 cycles.
Results: Non significant difference between the two groups regarding to the inptropic score and icu stay.
Conclusion: Both ischemic and pharmacological cardiac preconditioning could offer some sort of cardiac protection reflected upon inotropic score.

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The Medical Journal of Cairo University
Volume 86, September
September 2018
Pages 2361-2365

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