Male Sex as a Factor for Larger Size of Nodal Recurrence and More Tumor Burden (Advanced Disease Stage) in Recurrent Well Differentiated Thyroid Cancer

HAITHAM FEKRY, M.D., HOSSAM M. FAREED, M.Sc.;; MAGDY KOTB, M.D., TAREK EL-BARADIE, M.D.;; ISMAEEL A. MORAD, M.D., INAS EL-ATAR, M.D.;

doi:10.21608/mjcu.2018.57561

Male Sex as a Factor for Larger Size of Nodal Recurrence and More Tumor Burden (Advanced Disease Stage) in Recurrent Well Differentiated Thyroid Cancer

Document Type : Original Article

Authors

The Departments of Surgery*, Biostatistics** and Nuclear Medicine***, National Cancer Institute, Cairo

10.21608/mjcu.2018.57561

Abstract

Abstract
Background: Researchers have examined various factors that may affect recurrence and prognosis in Well Differentiated Thyroid Cancer (WDTC) such as age, sex, tumor size, and histological types. Also several studies tried to classify patients into low, medium and high risk in order to tailor adequate surgical and follow-up planes for each patient. The aim of our study was to study the effect of sex difference on nodal status and tumor burden.
Aim of Study: To assess effect of sex difference on size of affected lymph nodes in patients with recurrent well dif-ferentiated thyroid cancer.
Patients and Methods: Forty patients with recurrent (WDTC) were studied between June 2014 and June 2015, where adequate surgery was done, L.N. status was assessed pathologically and data was taken and statistically analyzed.
Results: Statistically significant different was found between both sex in relation to size of nodal recurrence in patient with recurrent (WDTC), where larger size of nodes were found in males. (p-value 0.034).
Conclusion: Male sex is an important factor with may affect burden of the disease, and size of nodal recurrence in patients with (WDTC) which may put those patients into higher risk group that needs special management and follow-up.

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