Effects of Immobilization Stress on Some Reproductive Functions in Adult Female Albino Rats

Abstract
Background: Various factors can disrupt the female re-productive cycle resulting in subfertility. Reproductive disor-ders and hazards to reproductive health have become prominent public health issue.
Aim of Work: Evaluation of the effects of immobilization stress on some reproductive functions in adult female albino rats.
Material and Methods: Twenty adult female albino rats of local strain weighing 145-160g were chosen to be the model of the present study. They were divided into two equal groups: Group I (Control group) received no treatment, and Group II (immobilization group) were subjected to immobilization stress for two weeks. Estrus cycle was examined by daily vaginal smear for determination of its phases. Blood samples were withdrawn and serum was separated for determination of FSH, LH, estrogen, progesterone, corticosterone, and prolactin serum levels.
Results: Chronic stress was associated with disturbed estrus cycle, gonadotrophic, estrogen, progesterone, corticos-terone, and prolactin hormones. Taken together these distur-bances affect the female reproductive functions.
Conclusion: Chronic stress has a drawback effects on the female reproductive functions. So, a great importance must be considered to avoid stressful situation aiming at avoidance of its drawback effects on the body functions.