Role of Laparoscopic Sleeve Gastrectomy (LSG) for Management of Obese Patients with Type 2 Diabetes Mellitus-Single Center Study

Abstract
Background: Laparoscopic Sleeve Gastrectomy (LSG) has become one of the commonest bariatric procedures done for management of obese patients. Although Laparoscopic Roux-en-Y Gastric Bypass (LRYGB) has well documented positive clinical influence on type 2 diabetes, the role of LSG in diabetes treatment is still questionable. In this study we want to present our experience in management of diabetes with LSG.
Methods: Between September 2014 and June 2016, fifty patients were enrolled in our prospective study at Department of Surgery, Ain Shams University assessing the effect of LSG on morbid obese patients with Type 2 Diabetes Mellitus (T2DM). All patients were monitored for weight loss and improvement of T2DM markers; Fasting Blood Glucose (FBG), Postprandial Plasma Glucose (PPG) and HbA1c at 3, 6 and 12 months follow-up post-operative.
Results: There was a highly significant difference between BMI at baseline and at 12 months after operation, resolution of type 2 diabetes mellitus occurred in 70% of patients evident by normalization of HbA1 c (5.6%) and stopping all medica-tions, and improvement occurred in 10% of patients evident by HbA1c value of 6.5% without medication.
Conclusion: Laparoscopic sleeve gastrectomy is simple and effective surgical procedure to achieve a significant weight loss and control of type 2 diabetes mellitus which starts in the early post-operative period. There is significant reduction in the diabetes medications hence the cost of diabetes treatment and improvement of the quality of life.