New Components in the Volatile Oil of Sage

Abstract Background: The volatile oil of dried leaves of "Sage" Salvia Officinalis was obtained by hydrodistillation (1.2% v/w). Aim of Study: This study was designed to analyze the volatile oil by (GC-MS). Material and Methods: Crushed dried Leaves (100g), were subjected to hydrodistillation E.P. (1984) GC-MS analysis was performed on Hewlett Packard 5850 GC connected to an HP 5970 quadruple nano spectrometer (70cw) and an HP 9000 work station with helium as the carrier gas. Results: 26 components representing 95% of the total oil were identified. Four of these components Linolool, Borneol, a-Terpinol and Thujone were most abundant constituents of the oil about (51%). In addition significant amounts of unre-ported constituents were found to be present such as peaks No. 12, 16, 17, 18 whose Mwt and preliminary chemical structure were suggested and called Kuwaitene 1,2,3,4 by author. Conclusion: GC-MS analysis of the volatile oil revealed at least 35 components, most of which could be identified, 4 of which were not reported in the literature before and reported here for the first time. (Peak No 12, 16, 17, 18 whose M. wts: 136 (1,4-Cyclohexanone, 1-Methyl 4, J-Methylethyl) 152 (Chrysanthone), 154 (3-Cyclohexen, 4-Methyl (I-Methyelthyl), 154 (Isomer) respectively).